Stricter treat-to-target in RA does not result in less radiographic progression: a longitudinal analysis in RA BIODAM.
Josef S SmolenRobert B M LandewéDésirée Mfm van der HeijdeAlexandre SeprianoOliver M FitzGeraldMikkel ØstergaardJoanne HomikOri ElkayamJ Carter ThroneMargaret J LarchéGianfranco FerraccioliMarina BackhausGilles BoireBernard G CombeThierry SchaeverbekeAlain SarauxMaxime DougadosMaurizio RossiniMarcello GovoniLuigi SinigagliaAlain G CantagrelCornelia F AllaartCheryl C M BarnabeClifton O BinghamDirkjan van SchaardenburgHilde Berner HammerRana DadashovaEdna HutchingsJoel PaschkeWalter P MaksymowychPublished in: Rheumatology (Oxford, England) (2023)
In this daily practice cohort, following T2T principles more meticulously did not result in less radiographic progression than a somewhat more lenient attitude toward T2T. One possible interpretation of these results is that the intention to apply T2T already suffices and that a more stringent approach does not further improve outcome.