Efficacy of palonosetron plus dexamethasone in preventing chemotherapy-induced nausea and emesis in patients receiving carboplatin-based chemotherapy for gynecologic cancers: a phase II study by the West Japan Gynecologic Oncology Group (WJGOG 131).
Shin NishioSatomi AiharaMototsugu ShimokawaAkira FujishitaShuichi TaniguchiToru HachisugaShintaro YanazumeHiroaki KobayashiFumihiro MurakamiFumitaka NumaKohei KoteraNaofumi OkuraNaoyuki TokiMasatoshi YokoyamaKimio UshijmaPublished in: Journal of gynecologic oncology (2018)
While palonosetron effectively controls acute CINV, additional antiemetic management is warranted in the delayed phase after carboplatin-based chemotherapy in gynecologic cancer patients (Trial registry at UMIN Clinical Trials Registry, UMIN000012806).
Keyphrases
- chemotherapy induced
- phase ii study
- open label
- clinical trial
- locally advanced
- phase iii
- phase ii
- endometrial cancer
- placebo controlled
- liver failure
- study protocol
- rectal cancer
- low dose
- respiratory failure
- drug induced
- radiation therapy
- high dose
- aortic dissection
- hepatitis b virus
- intensive care unit
- extracorporeal membrane oxygenation