Vancomycin area under the curve-guided monitoring in pediatric patients.
Ronaldo Morales JuniorVanessa D'Amaro JuodinisIsabela Cristina Pinheiro de Freitas SantosCamila Canuto CampioniFlávia Gatto de Almeida WirthLivia Maria Goncalves BarbosaDaniela Carla de SouzaSilvia Regina Cavani Jorge SantosPublished in: Revista Brasileira de terapia intensiva (2022)
Most patients did not reach the therapeutic target with a vancomycin empirical dose regimen, and the implementation of area under the curve-based dosing using two sample measurements allowed for real-time dose adjustments based on individuals' pharmacokinetic parameters.