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The Effect of Vascular Endothelial Growth Factor C and Adipose-Derived Stem Cells on Lymphatic Regeneration in a Rat Vascularized Lymph Node Transfer Model.

Filip JonasPeter KesaPetr ParalJan PankracMarie Hubalek KalbacovaJakub MiletinAndrej SukopMartin MolitorKrystof StanekLudek SefcOndrej Mestak
Published in: Journal of reconstructive microsurgery (2022)
 We found that the fastest regeneration occurred with the combination of the VLN flap and VEGF-C. The addition of ADSC had an insignificant effect in our study. Furthermore, we proved the feasibility of PAI as an assessment tool of the lymphatic drainage recovery in a VLNT model.
Keyphrases
  • vascular endothelial growth factor
  • lymph node
  • stem cells
  • endothelial cells
  • wound healing
  • neoadjuvant chemotherapy
  • sentinel lymph node
  • oxidative stress
  • early stage
  • soft tissue