Use of DNA-alkylating pyrrole-imidazole polyamides for anti-cancer drug sensitivity screening in pancreatic ductal adenocarcinoma.

Akiko TsujimotoNiina MatsuoXiaoyi LaiTakahiro InoueHiroyuki YodaJason LinYoshinao ShinozakiTakayoshi WatanabeNobuko KoshikawaAtsushi TakatoriHiroki Nagase

Published in: Cancer medicine (2022)

These data suggested that the simultaneous inhibition of RAD51 and mutant KRAS blockage would be an important therapeutic strategy for PDAC.

Keyphrases

wild type
circulating tumor
electronic health record
dna damage
dna repair
cell free
single molecule
big data
adverse drug
emergency department
nucleic acid
drug induced
artificial intelligence
data analysis
oxidative stress