A Data-Driven Approach to Predicting 5-Aminolevulinic Acid-Induced Fluorescence and World Health Organization Grade in Newly Diagnosed Diffuse Gliomas.

Michael MütherMohammed JaberTimothy D JohnsonDaniel A OrringerWalter Stummer

Published in: Neurosurgery (2022)

We demonstrate a strong correlation between enhancement on preoperative MRI and the likelihood of visible fluorescence during surgery in patients with intermediate-grade glioma. Our analysis provides a robust method for predicting 5-ALA-induced fluorescence in patients with grade II and grade III gliomas.

Keyphrases

newly diagnosed
single molecule
high grade
energy transfer
magnetic resonance imaging
minimally invasive
low grade
high glucose
diabetic rats
magnetic resonance
acute coronary syndrome
endothelial cells
surgical site infection
diffusion weighted imaging