Systematic Study on the Catalytic Arsa-Wittig Reaction.

Ryoto InabaIkuo KawashimaToshiki FujiiTakashi Yumura Hiroaki Imoto Kensuke Naka

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)

Efficient catalytic arsa-Wittig reactions have been developed by using 1-phenylarsolane as a catalyst. A wide array of aldehydes was converted to the corresponding olefins in high yields with moderate to excellent E stereoselectivity in the presence of a catalytic amount of 1-phenylarsolane. Moreover, density functional theory calculations were carried out to afford insight into the E/Z selectivity.

Keyphrases

density functional theory
molecular dynamics
crystal structure
high resolution
high throughput
room temperature
high intensity
highly efficient
high density