Reducing the red blood cell transfusion threshold from 8·0 g/dl to 7·0 g/dl in acute myeloid leukaemia patients undergoing induction chemotherapy reduces transfusion rates without adversely affecting patient outcome.
Olivier BalloPhiline FleckensteinFagr EladlyEva-Maria KreiselJan StratmannErhard SeifriedMarkus MüllerHubert ServeGesine BugHalvard BonigChristian H BrandtsFabian FinkelmeierPublished in: Vox sanguinis (2020)
From our retrospective analysis, we conclude that a more restrictive transfusion trigger does not affect important outcomes of AML patients. The opportunity to test possible effects of the more severe anaemia in the restrictive transfusion group on quality of life was missed.
Keyphrases
- cardiac surgery
- red blood cell
- sickle cell disease
- patients undergoing
- end stage renal disease
- acute myeloid leukemia
- ejection fraction
- newly diagnosed
- acute kidney injury
- liver failure
- prognostic factors
- peritoneal dialysis
- bone marrow
- dendritic cells
- early onset
- respiratory failure
- radiation therapy
- immune response
- insulin resistance
- hepatitis b virus
- intensive care unit
- acute lymphoblastic leukemia
- aortic dissection
- adipose tissue
- weight loss