DNA methylation of the Lamin A/C gene is associated with congenital heart disease.

Nandini Mukherjee Elijah Holbrook BolinAmna QasimMohammed S OrloffPhilip J Lupo Wendy N Nembhard

Published in: Birth defects research (2024)

We identify statistically significant differences in LMNA DNAm between CHD cases and controls. Future studies should investigate the role of maternal LMNA DNAm in CHD development.

Keyphrases

dna methylation
genome wide
nk cells
muscular dystrophy

copy number
gene expression
current status
birth weight

pregnancy outcomes
case control
genome wide identification
pregnant women

duchenne muscular dystrophy
body mass index
weight loss