The Establishment of a Mouse Model for Degenerative Kyphoscoliosis Based on Senescence-Accelerated Mouse Prone 8.

Zongshan HuZiyang TangAbdukahar KiramJie LiHui XuYanjie XuHuiming JiangZezhang ZhuYong QiuZhen Liu

Published in: Oxidative medicine and cellular longevity (2022)

The SAMP8 mouse model can be taken as a clinically relevant model of DKS, and accelerated aging of the musculoskeletal system promotes the development of kyphosis.

Keyphrases

mouse model
dna damage
endothelial cells
stress induced