Polysaccharides from steam-processed Polygonatum cyrtonema Hua protect against d-galactose-induced oxidative damage in mice by activation of Nrf2/HO-1 signaling.

Huanhuan TengYi ZhangChuanshan JinTongsheng WangShengzhuo HuangLei LiJian-Ping LuoDeling WuFengqing Xu

Published in: Journal of the science of food and agriculture (2022)

Overall, the results suggest that PCPS has a stronger effect on the prevention of oxidative damage by activating Nrf2/HO-1 antioxidant signaling. This study demonstrates the role of steam-processed P. cyrtonema rhizome and provides valuable perspective for PCPS as a functional agent. © 2022 Society of Chemical Industry.

Keyphrases

oxidative stress
diabetic rats
signaling pathway
pi k akt
high glucose
anti inflammatory
high fat diet induced
adipose tissue
skeletal muscle
insulin resistance