Early diarrhoea under sorafenib as a marker to consider the early migration to second-line drugs.
Álvaro Díaz-GonzálezVíctor SapenaLoreto BoixFerràn TorresMarco Sanduzzi-ZamparelliLeonardo Gomes da FonsecaNeus LlarchGemma IserteCassia GuedesSergio Muñoz-MartínezAnna DarnellErnest BelmonteJordi RimolaAlejandro FornerCarmen AyusoJordi BruixMaria ReigPublished in: United European gastroenterology journal (2021)
The emergence of e-diarrhoea in HCC patients treated with sorafenib is an early predictor of dismal evolution under this therapy. Thus, prompt identification of these non-responders may be useful for an early switch to second-line therapies.
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