Towards a better understanding of adult idiopathic epidermal necrolysis: a retrospective study of 19 cases.
P MonnetC RodriguezO GaudinP CirotteauB PapouinOlivier DereureF TetartSophie LalevéeA ColinB Lebrun-VignesE AbeJ-C AlvarezV DemontantG GricourtN de ProstC BarauO ChosidowP WolkensteinS HueNicolas OrtonneBrigitte MilpiedSaskia Ingen Housz OroPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2021)
IEN affects young people and is a severe form of EN. A large toxicologic investigation is warranted. Different pathways seem involved in IEN and DIEN, leading to the same apoptotic effect, but the primary trigger remains unknown.