The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase.
Eva Monte-SerranoPatricia Morejon-GarciaIgnacio Campillo-MarcosAurora Campos-DíazElena Navarro-CarrascoPedro A LazoPublished in: Epigenetics & chromatin (2023)
The chromatin kinase VRK1 regulates the epigenetic patterns of histone H3 acetylation and methylation in lysines 4, 9 and 27. VRK1 is a master regulator of chromatin organization associated with its specific functions, such as transcription or DNA repair.