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Progression of multiple vertebral fractures after denosumab discontinuation under treatment with romosozumab. A case-report.

Michail KrikelisSusana GaziGeorgios TrovasKonstantinos MakrisEfstathios ChronopoulosSymeon Tournis
Published in: Joint bone spine (2024)
Our clinical case illustrates the ineffectiveness of Rmab to prevent the multiple vertebral fracture cascade attributable to discontinuation of Dmab. We believe that treatment with Rmab might not be enough to prevent this phenomenon. Treatment with Dmab or possibly combination treatment with Dmab and Rmab could be another treatment option.
Keyphrases
  • combination therapy