Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA.
Xiaoji ChenZhao DongEarl HubbellKathryn N KurtzmanGeoffrey R OxnardOliver VennCollin MeltonChristina A ClarkeRita ShaknovichTing MaGerry MeixiongMichael V SeidenEric E KleinEric T FungMinetta C LiuPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Cancer detection by the MCED test was prognostic beyond clinical stage and method of diagnosis. Cancers not detected by the MCED test had better prognosis than cancers detected and SEER-based expected survival. Cancer detection and prognosis may be linked by the underlying biological factor of tumor fraction in cfDNA.