Transitioning to molecular diagnostics in pediatric high-grade glioma: experiences with the 2016 WHO classification of CNS tumors.
Joshua N BaughGerrit H GielenDannis G van VuurdenSophie E M Veldhuijzen van ZantenDarren HargraveMaura MassiminoVeronica BiassoniAndres Morales la MadridMichael KarremannMaria WieseUlrich ThomaleGeert O JanssensAndré O von BuerenThomas PerweinEelco W HovingTorsten PietschFelipe AndreiuoloChristof M KrammPublished in: Neuro-oncology advances (2021)
Our findings demonstrate an overall greater reliance and favorability to molecular diagnostics among very high development countries. A disparity in resources and access to molecular diagnostics has left some centers unable to classify pediatric high-grade glioma per the WHO classification. The forthcoming edition should strain to abate disparities in molecular diagnostic availability and work toward universal adaptation.