Right ventrolateral and left dorsolateral 10 Hz transcranial magnetic stimulation as an add-on treatment for bipolar I and II depression: a double-blind, randomised, three-arm, sham-controlled study.

Tomáš Novák Lenka Kostýlková Martin Bares Veronika Voráčková Martin HejzlarJiří RenkaSilvie BaumannOlga Laskov Monika Klírová

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2024)

While not demonstrating the superiority of either 10 Hz rTMS over sham, with the limited sample size, we can not rule out a moderate yet clinically meaningful effect. Further well-powered studies are essential to elucidate the role of rTMS in managing BDE.

Keyphrases

transcranial magnetic stimulation
high frequency
double blind
clinical trial
open label
depressive symptoms
placebo controlled
bipolar disorder
study protocol
sleep quality
case control