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Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.

Daniel J St-CyrDerek F CeccarelliStephen OrlickyAlmer M van der SlootXiaojing TangSusan KelsoSusan MooreClint JamesGanna PosternakJasmin Coulombe-HuntingtonThierry BertomeuAnne MarinierFrank SicheriMike Tyers
Published in: Science advances (2021)
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Keyphrases
  • smoking cessation
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  • single molecule