Limitations of biopsy-based transcript diagnostics to detect T cell-mediated allograft rejection.
Lukas WeidmannDusan HarmacekKai Castrezana LopezBirgit Maria HelmchenAriana GaspertRaphael KorachNicola BortelNicolas SchmidSeraina von MoosElena RhoThomas SchachterPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)
MMDx did not identify pure mTCMR among Isolated Tubulitis, Borderline Changes, or Isolated Arteritis, likely due to low sensitivity for TCMR-lesions. However, it identified mAMR or mAMR/TCMR, especially in cases with MVI. Subthreshold findings remain to be further studied.
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