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Associations Between Blood-Based Biomarkers and Cognitive and Functional Trajectories Among Participants of the MEMENTO Cohort.

Leslie GrassetVincent BouteloupFederica CacciamaniIsabelle PellegrinVincent PlancheGenevieve CheneCarole Dufouilnull null
Published in: Neurology (2024)
In a memory clinic sample, p-tau181 and NfL, both independently and jointly, are linked to more pronounced cognitive, physical and functional declines. Blood-based biomarker measurement in AD research may provide useful insights regarding biological processes underlying cognitive, physical, and functional declines in at-risk individuals.
Keyphrases
  • physical activity
  • mental health
  • primary care
  • depressive symptoms
  • cerebrospinal fluid