Associations of Proteomics With Hypertension and Systolic Blood Pressure: KORA S4/F4/FF4 and KORA Age1/Age2 Cohort Studies.
Jie-Sheng LinAgnese PetreraStefanie M HauckChristian L MüllerAnnette PetersBarbara ThorandPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
We identified and validated 7 hypertension-associated and 23 SBP-associated proteins across 2 cohort studies. KIM1, NT-proBNP, and OPG demonstrated robust associations, and OPG was identified for the first time as associated with blood pressure. For NT-proBNP (protective) and OPG, causal associations with SBP were suggested.