Reconstruction of time-consistent species trees.
Manuel LafondMarc HellmuthPublished in: Algorithms for molecular biology : AMB (2020)
In this contribution, we consider event-labeled gene trees that contain speciations, duplications as well as horizontal gene transfer (HGT) and we assume that the species tree is unknown. Although many problems become NP-hard as soon as HGT and time-consistency are involved, we show, in contrast, that the problem of finding a time-consistent species tree for a given event-labeled gene can be solved in polynomial-time. We provide a cubic-time algorithm to decide whether a "time-consistent" species tree for a given event-labeled gene tree exists and, in the affirmative case, to construct the species tree within the same time-complexity.