Binding modes of high stoichiometry guest complexes with a Co 8 L 12 cage uncovered by mass spectrometry.

Daniel L StaresCristina MozaceanuMichael D Ward Christoph A Schalley

Published in: Chemical communications (Cambridge, England) (2023)

We demonstrate how different modes of guest binding with a Co 8 L 12 cubic cage can be determined using ESI-MS. High stoichiometry guest binding was observed, with the guests preferentially binding externally, but internal guest inclusion was also seen at higher guest loading.

Keyphrases

mass spectrometry
water soluble
ms ms
dna binding
binding protein
multiple sclerosis
liquid chromatography