Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: a case report.

Hiroshi HongoTakeo KosakaEriko AimonoHiroshi NishiharaMototsugu Oya

Published in: Diagnostic pathology (2020)

We describe a case of aggressive, castration-resistant prostate cancer with FANCA homodeletion. Genomic analysis of prostate cancer tissue can be useful to determine optimal treatment of such cancers.

Keyphrases

prostate cancer
copy number
radical prostatectomy
dna repair
dna damage
genome wide
dna methylation
oxidative stress
combination therapy
transcription factor
genome wide analysis