The invariant arginine within the chromatin-binding motif regulates both nucleolar localization and chromatin binding of Foamy virus Gag.

Joris ParisJoëlle Tobaly-TapieroMarie-Lou GironJulien Burlaud-GaillardFlorence BuseynePhilippe RoingeardPascale LesageAlessia ZamborliniAli Saïb

Published in: Retrovirology (2018)

Altogether, our findings suggest that methylation by PRMT1 might finely tune the subnuclear distribution of Gag depending on the stage of the FV replication cycle. The role of this step for viral replication remains an open question.

Keyphrases

genome wide
dna damage
gene expression
transcription factor
dna binding
dna methylation
sars cov
nitric oxide
binding protein
amino acid