UNC-5 netrin receptor B regulates adipogenesis of human adipose-derived stem cells through JNK pathway.

Xinyi HuXuejiao LiuLongwei LvXiao ZhangYunsong LiuYongsheng Zhou Yongsheng Zhou

Published in: Journal of oral rehabilitation (2020)

Our findings showed that UNC5B inhibited adipogenesis of hASCs through JNK signalling. As a whole, UNC5B regulates both adipogenesis and osteogenesis of hASCs.

Keyphrases

signaling pathway
high fat diet induced
cell death
endothelial cells
induced apoptosis
induced pluripotent stem cells
insulin resistance
type diabetes
wound healing