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Incidence, risk factors, and clinical outcomes of HBV reactivation in non-liver solid organ transplant recipients with resolved HBV infection: A systematic review and meta-analysis.

Saifu YinFan ZhangJiapei WuTao LinXianding Wang
Published in: PLoS medicine (2023)
Non-liver SOT recipients with resolved HBV infection have a high risk of HBV-related hepatic failure and HBV-related death if HBV reactivation occurs. Potential risk factors for HBV reactivation include rituximab use, anti-thymocyte immunoglobulin use, anti-HBs negative status, acute rejection history, and ABO blood type-incompatible transplantation. Further research on monitoring and routine antiviral prophylaxis of non-liver SOT recipients at higher risk of HBV reactivation is required.
Keyphrases
  • hepatitis b virus
  • liver failure
  • risk factors
  • mesenchymal stem cells
  • clinical practice
  • climate change
  • human health