Cytotoxic and targeted systemic therapy in patients with advanced cutaneous squamous cell carcinoma in the head and neck.
Samantha TamMona GajeraXiaoning LuoBonnie S GlissonRenata FerrarottoFaye M JohnsonFrank E MottMaura L GillisonCharles LuXiuning LeGeorge R BlumenscheinMichael K WongDavid I RosenthalPriyadharsini NagarajanAdel K El-NaggarMichael R MidgenRandal S WeberJeffrey N MyersNeil D GrossPublished in: Head & neck (2021)
Survival was worse in M1 patients treated with cytotoxic or targeted systemic therapy and poor baseline performance status but improved in those receiving radiotherapy. These data can serve as historical controls for future systemic therapy trials, including immunotherapy.