Cluster analysis of clinical manifestations assigns systemic lupus erythematosus-phenotype subgroups: A multicentre study on 440 patients.

Fanny MarietteVéronique Le GuernYann NguyenCécile YelnikNathalie MorelEric HachullaMarc LambertGaëlle Guettrot-ImbertLuc MouthonMikael EbboNathalie Costedoat-Chalumeau

Published in: Joint bone spine (2024)

This unsupervised clustering method distinguished three distinct SLE patient subgroups, highlighting SLE heterogeneity.

Keyphrases

systemic lupus erythematosus
disease activity
end stage renal disease
single cell
ejection fraction
chronic kidney disease
newly diagnosed
machine learning
case report
prognostic factors
rna seq
patient reported outcomes