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Definitive chemoradiotherapy induces T-cell-inflamed tumor microenvironment in unresectable locally advanced esophageal squamous cell carcinoma.

Takumi HabuShogo KumagaiHideaki BandoTakeshi FujisawaSaori MishimaDaisuke KotaniMasaki NakamuraHidehiro HojoShingo SakashitaTakahiro KinoshitaTomonori YanoShuichi MitsunagaHiroyoshi NishikawaSyohei KoyamaTakashi Kojima
Published in: Journal of gastroenterology (2024)
T cells as a predictive factor for prognosis. This finding supports the rationale for the necessity of subsequent PD-1 inhibitor treatment.
Keyphrases
  • locally advanced
  • rectal cancer
  • neoadjuvant chemotherapy
  • squamous cell carcinoma
  • radiation therapy
  • phase ii study
  • clinical trial
  • lymph node
  • replacement therapy