The Efficacy of Anti-Tumor Necrosis Factor Therapy in Cryopyrin-Associated Periodic Syndromes: A Report of Two Cases.

Fatemeh Tahghighi Mahdieh Vahedi Nima Parvaneh Mohammad Shahrooei Vahid Ziaee

Published in: Case reports in genetics (2022)

IL-1 inhibitors are highly effective in treating CAPS patients. Most patients with severe symptoms such as neurologic involvement improve with IL-1 blockade. Anti-TNF agents might be effective in reducing mild manifestation; however, they are not effective in improving more severe complications.

Keyphrases

end stage renal disease
rheumatoid arthritis
ejection fraction
newly diagnosed
chronic kidney disease
early onset
peritoneal dialysis
stem cells
drug induced
bone marrow
sleep quality
depressive symptoms
smoking cessation