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A modified LI-RADS: targetoid tumors with enhancing capsule can be diagnosed as HCC instead of LR-M lesions.

Ji Hye MinJong Man KimYoung Kon KimHonsoul KimGyu Seong ChoiTae Wook KangDongik ChaJeong Ah HwangSeong Eun KoSoohyun Ahn
Published in: European radiology (2021)
• By conventional LI-RADS, 31 (16.0%) of 194 HCCs were categorized as LR-M. • Among 31 HCCs categorized as LR-M, 19 HCCs or 8 HCCs were recategorized as HCC on ECA-MRI or HBA-MRI, respectively, after applying the modified LR-5 category, which allocates targetoid lesions with enhancing capsule as mLR-5C instead of LR-M. • The mLR-5C showed superior sensitivity compared with the LR-5 in both MRIs (ECA-MRI, 76.6% vs. 67.0%; HBA-MRI, 60.4% vs. 56.3%, both p < 0.05), while maintaining high specificity (ECA-MRI, 93.8% vs. 98.4%; HBA-MRI, 95.3% vs. 98.4%; both p > 0.05).
Keyphrases
  • contrast enhanced
  • magnetic resonance imaging
  • diffusion weighted imaging
  • computed tomography
  • structural basis