Outcomes of Lymph Node Dissection in Nephroureterectomy in the Treatment of Upper Tract Urothelial Carcinoma: Analysis of the ROBUUST Registry.
Kevin HakimiUmberto CarbonaraHooman DjaladatReza MehrazinDaniel EunAdam ReeseMark L GonzalgoVitaly MargulisRobert G UzzoJames PorterChandru P SundaramFiras AbdollahAlexandre MottrieRiccardo TelliniMatteo FerroArman WaliaAva SaidianShady SolimanJulia YuanAlessandro VecciaAlireza GhoreifiGiovanni CacciamaniAmit S BhattuXiaosong MengJason M FarrowMarcus JamilAndrea MinerviniKoon H RhaZhenjie WuGiuseppe SimoneRiccardo AutorinoIthaar H DerweeshPublished in: The Journal of urology (2022)
LND during nephroureterectomy in patients with positive lymph nodes provides prognostic data, but is not associated with improved OS. LND yields ≥10 in patients with clinical node negative disease were associated with improved RFS. In high-grade and large tumors, lymphadenectomy should be considered.