Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes.
Nina GollNina MoszkaKonstantinos KantartzisHubert PreisslTim GruberLouise FritscheReiner Jumpertz-von SchwarzenbergCristina García-CáceresAndreas FritscheManfred HallschmidPublished in: Diabetes, obesity & metabolism (2024)
This outcome contrasts with the oxytocin-induced attenuation of early postprandial glucose excursions in normal-weight individuals, but is in line with the absence of respective effects in men with obesity. We conclude that insulin resistance in type 2 diabetes is associated with decreased sensitivity to the acute glucoregulatory effect of oxytocin in male individuals.
Keyphrases
- type diabetes
- weight loss
- blood glucose
- insulin resistance
- drug induced
- weight gain
- middle aged
- liver failure
- glycemic control
- metabolic syndrome
- body mass index
- high glucose
- diabetic rats
- physical activity
- respiratory failure
- cardiovascular disease
- high fat diet induced
- hepatitis b virus
- aortic dissection
- mechanical ventilation