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Liver function assessment using indocyanine green plasma disappearance rate in a young male with icteric leptospirosis: a case report.

Alicja J KunikowskaMonika WildgruberEwert Schulte-FrohlindeTobias LahmerRoland M SchmidWolfgang Huber
Published in: BMC infectious diseases (2019)
Markedly diminished ICG-PDR values presented in this case report suggest severe liver function impairment in the acute phase of icteric leptospirosis. Prolonged elevation of serum bilirubin may not adequately reflect recovery of liver injury in this disease. ICG clearance appears to be a promising marker for the detection of hepatic dysfunction and recovery in icteric leptospirosis in addition to the static tests.
Keyphrases
  • liver injury
  • drug induced
  • case report
  • fluorescence imaging
  • oxidative stress
  • loop mediated isothermal amplification
  • photodynamic therapy
  • real time pcr