Toll-like Receptor Signaling-deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing.

Álvaro Morales-Molina Miguel Ángel Rodríguez-Milla Stefano Gambera Teresa Cejalvo Belén de Andrés María-Luisa Gaspar Javier García-Castro

Published in: Cancer research communications (2023)

Cells carrying drugs, virus, or other antitumor agents are commonly used for the treatment of cancer. This research shows that silent cells are excellent carriers for immunotherapies, improving tumor homing and enhancing the antitumor effect.

Keyphrases

induced apoptosis
toll like receptor
cell cycle arrest
endoplasmic reticulum stress
cell death
oxidative stress
nuclear factor
single cell
drug induced