Determinants of cerebral radiological progression in Fabry disease.

Simon KörverMaria G F LongoMarjana R LimaCarla E M HollakMohamed El SayedIvo N van SchaikLeonardo VedolinMarcel G W DijkgraafMirjam Langeveld

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

Progression of WMLs and cerebral infarctions in FD is mainly related to age, sex and phenotype. Additional effects of established cardiovascular risk factors, organ involvement and treatment with ERT are probably small to negligible.

Keyphrases

cardiovascular risk factors
subarachnoid hemorrhage
cardiovascular disease
metabolic syndrome
replacement therapy
cerebral ischemia
type diabetes
hypertrophic cardiomyopathy
combination therapy
cerebral blood flow
left ventricular
drug induced