Transcriptional Behavior of Regulatory T Cells Predicts IBD Patient Responses to Vedolizumab Therapy.

Maria T AbreuJulie M DaviesMaria A QuinteroAmber DelmasSophia DiazCatherine D MartinezThomas VenablesAdrian ReichGogce CrynenAmar R DeshpandeDavid H KermanOriana M DamasIrina FernandezAna M SantanderJudith Pignac-KobingerJuan F BurguenoMark S Sundrud

Published in: Inflammatory bowel diseases (2022)

Mucosal and peripheral blood immune cell phenotypes and transcriptional profiles can inform VDZ efficacy and inform new opportunities for combination therapies.

Keyphrases

regulatory t cells
peripheral blood
ulcerative colitis
gene expression
dendritic cells
transcription factor
case report
heat shock
patients with inflammatory bowel disease
stem cells
heat stress