MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages.
Renumathy DhanasekaranAida S HansenJangho ParkLea LemaitreIan LaiNia AdenijiSibu P KuruvillaAkanksha SureshJosephine ZhangVarsha SwamyDean W FelsherPublished in: Cancer research (2023)
Macrophage-mediated immune evasion is a therapeutic vulnerability of MYC-driven cancers, which has implications for prioritizing MYC-driven hepatocellular carcinoma for combination immunotherapy.