Immunological classification of renal cell carcinoma patients based on phenotypic analysis of immune check-point molecules.
Atsunari KawashimaTakayuki KanazawaKumiko GotoMitsunobu MatsumotoAkiko Morimoto-OkazawaKota IwahoriTakeshi UjikeAkira NagaharaKazutoshi FujitaMotohide UemuraNorio NonomuraHisashi WadaPublished in: Cancer immunology, immunotherapy : CII (2017)
This study showed that the presence of classable diversity in the immunological signature of tumour tissue-infiltrating lymphocytes correlated with prognosis and tumour aggressiveness that was observed even within individual tumours in some patients with renal cell carcinoma.