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Liposome triggered content release through molecular recognition of inositol trisphosphate.

Sydney E BottcherJinchao LouMichael D Best
Published in: Chemical communications (Cambridge, England) (2022)
A stimuli-responsive liposomal platform that is selectively activated by inositol 1,4,5-trisphosphate (IP 3 ) over eleven other phosphorylated metabolites is reported. Dye release assays validated dose-dependent release of both hydrophilic and hydrophobic cargo driven by IP 3 , showcasing the potential of this platform for triggered release and sensing applications.
Keyphrases
  • high throughput
  • liquid chromatography
  • risk assessment
  • high resolution
  • simultaneous determination