Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function.

Hao-Wei LeeSzu-Jung ChenKuen-Jer TsaiKuei-Sen HsuYi-Fan ChenChih-Hua ChangHsiao-Han LinWen-Yun HsuehHsing-Pang HsiehYueh-Feng LeeHuai-Chueh ChiangJang-Yang Chang

Published in: Journal of biomedical science (2024)

influx, leading to enhanced activation of the BDNF/TrkB axis. Our study may provide a novel strategy for improving cognitive function by targeting CTSS.

Keyphrases

cancer therapy
stress induced