Vitamin D Status, VDR, and TLR Polymorphisms and Pulmonary Tuberculosis Epidemiology in Kazakhstan.

Dauren Yerezhepov Aidana GabdulkayumAinur AkhmetovaUlan A KozhamkulovSaule E RakhimovaUlykbek Y KairovGulnur ZhunussovaRuslan N Kalendar Ainur R Akilzhanova

Published in: Nutrients (2024)

, and diabetes are the main risk factors for the development of pulmonary TB in our study. A/A polymorphism of TLR8 (rs3764880) and T/T polymorphism (BsmI, rs1544410) of VDR genes may act as biomarkers for pulmonary tuberculosis in the Kazakh population.

Keyphrases

pulmonary tuberculosis
mycobacterium tuberculosis
toll like receptor
inflammatory response
immune response
type diabetes
cardiovascular disease
pulmonary hypertension
genome wide
risk factors
nuclear factor
gene expression
dna methylation
skeletal muscle
genome wide analysis