Insulin Therapy on Bone Macroscopic, Microarchitecture, and MechanicalProperties of Tibia in Diabetic Rats.

Pedro Henrique Justino Oliveira LimirioNilson Ferreira De Oliveira NetoJessyca Figueira VenâncioCamila Rodrigues Borges LinharesPriscilla Barbosa Ferreira SoaresPaula Dechichi

Published in: Current diabetes reviews (2024)

T1DM reduces bone growth and mechanical strength. Insulin therapy in diabetic rats improved bone growth and fracture resistance, making diabetic bone similar to normoglycemic animals.

Keyphrases

diabetic rats
bone mineral density
oxidative stress
type diabetes
soft tissue
bone loss
bone regeneration
postmenopausal women
glycemic control
stem cells
body composition
mesenchymal stem cells
cell therapy