The trajectories of depression symptoms and comorbidity in knee osteoarthritis subjects.
Mingyang LiYong NieYi ZengYuangang WuYuan LiuLimin WuShen BinPublished in: Clinical rheumatology (2021)
A significant amount of KOA subjects tends to develop depression symptoms and comorbidity. Managing related risk factors, like weight loss or smoking cessation, might have considerable significance in preventing or delaying depression symptoms and comorbidity in KOA. Key Points • The first study investigating the trajectory of comorbidity progression in KOA. • Approximately 7.5% of KOA patients tend to develop depression symptoms quite rapidly, and 30% of KOA patients tend to develop comorbidity • Risk factors of worsening trajectories were identified: obesity, older age, smoking, female, and lower income.
Keyphrases
- depressive symptoms
- sleep quality
- smoking cessation
- risk factors
- end stage renal disease
- knee osteoarthritis
- weight loss
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- peritoneal dialysis
- metabolic syndrome
- bariatric surgery
- insulin resistance
- patient reported
- weight gain
- skeletal muscle
- gastric bypass
- patient reported outcomes
- obese patients