In vitro model reveals a role for mechanical stretch in the remodeling response of lymphatic muscle cells.

Joshua S T HooksCristina C ClementHoang-Dung NguyenLaura SantambrogioJ Brandon Dixon

Published in: Microcirculation (New York, N.Y. : 1994) (2018)

LMCs exist on a functional spectrum, becoming more active in response to stretching and maintaining phenotypic remodeling in response to local lymphatic/tissue damage.

Keyphrases

lymph node
induced apoptosis
cell cycle arrest
oxidative stress
skeletal muscle
endoplasmic reticulum stress
signaling pathway