Ovarian Tumor Domain-Containing 7B Attenuates Pathological Cardiac Hypertrophy by Inhibiting Ubiquitination and Degradation of Krüppel-Like Factor 4.
Bin-Bin DuJie-Lei ZhangLing-Yao KongHui-Ting ShiDian-Hong ZhangXing WangChun-Lei YangPeng-Cheng LiRui YaoCui LiangLei-Ming WuZhen HuangPublished in: Journal of the American Heart Association (2023)
These results demonstrate that the OTUD7B-KLF4 axis is a novel molecular target for CH treatment.