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Distinguishing mechanisms underlying EMT tristability.

Dongya JiaMohit Kumar JollySatyendra C TripathiPetra Den HollanderBin HuangMingyang LuMuge CeliktasEsmeralda Ramirez-PeñaEshel Ben-JacobJosé N OnuchicSamir M HanashSendurai A ManiHerbert Levine
Published in: Cancer convergence (2017)
These experimental results argue in favor of the TCS model proposing that miR-200/ZEB1 behaves as a three-way decision-making switch enabling transitions among the E, hybrid E/M and M phenotypes.
Keyphrases
  • epithelial mesenchymal transition
  • long non coding rna
  • decision making
  • cell proliferation
  • long noncoding rna
  • signaling pathway