Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease.

Caitlyn VlasschaertAmy J M McNaughtonMichael ChongElina K CookWilma HopmanBryan R Kestenbaum Cassianne Robinson-CohenJocelyn GarlandSarah M MoranGuillaume ParéCatherine M Clase Mila TangAdeera LevinRachel HoldenMichael J RauhMatthew B Lanktree

Published in: Journal of the American Society of Nephrology : JASN (2022)

In this exploratory analysis of individuals with preexisting CKD, CHIP was associated with higher baseline KFRE scores, greater progression of CKD, and anemia. Further research is needed to define the nature of the relationship between CHIP and kidney disease progression.

Keyphrases

chronic kidney disease
end stage renal disease
high throughput
circulating tumor cells
risk assessment
fine needle aspiration
climate change
ultrasound guided